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KMID : 1035220100020010021
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Korean Journal of Neuromuscular Disorders
2010 Volume.2 No. 1 p.21 ~ p.25
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Inclusion Body Myositis
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Seo Kyung-Im
Hong Ji-Man
Choi Young-Chul
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Abstract
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Inclusion body myositis (IBM) is the most common idiopathic inflammatory myositis in patients over the age of 50 years. Prevalence of IBM varies among countries and ethnic groups. Etiology and pathogenesis of IBM is still unknown. It may be primary degenerative myopathy or autoimmune inflammatory myopathy or both. Asymmetrical weakness of the quadriceps and flexor forearm muscles are the clinical key of IBM. This review covers clinical presentation, pathogenesis, diagnosis and treatment of IBM.
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KEYWORD
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Inclusion body myositis, Sporadic inclusion body myositis, Idiopathic inflammatory myositis, Muscle biopsy
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